tetracycline


tetracycline
/te'treuh suy"kleen, -klin/, n. Pharm.
an antibiotic, C22H24H2O8, derived from chlortetracycline, used in medicine to treat a broad variety of infections.
[1950-55; TETRA- + CYCL- + -INE]

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Any of a class of broad-spectrum antibiotics with a common basic structure, including doxycycline.

They may be isolated directly from several species of actinomycetes of the genus Streptomyces or modified from the compounds isolated. They are the drugs of choice in the treatment of cholera, rickettsial infections (see rickettsia), psittacosis, brucellosis, and tularemia; tetracyclines are also used in the treatment of acne. Overuse of these and other antibiotics has led to drug resistance in microorganisms.

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▪ antibiotic group
      any of a group of broad-spectrum antibiotic compounds that have a common basic structure and are either isolated directly from several species of Streptomyces bacteria or produced semisynthetically from those isolated compounds. Tetracyclines act by interfering with the ability of a bacterium to produce certain vital proteins; thus they are inhibitors of growth (bacteriostatic) rather than killers of the infectious agent (bacteriocidal) and are effective only against multiplying microorganisms. Tetracyclines are used against a variety of infectious diseases, including cholera, rickettsial infections, trachoma (a chronic infection of the eye), psittacosis (a disease transmitted by certain birds), brucellosis, and tularemia. Tetracyclines have also been used for the treatment of acne. By the late 20th century, concerns arose that the widespread use of tetracyclines was contributing to an increase in the number of tetracycline-resistant organisms, which in turn had rendered certain infections more resilient to treatment. The use of tetracyclines in livestock feed to promote growth was also called into question.

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Universalium. 2010.

Look at other dictionaries:

  • Tetracycline — (eingedeutscht Tetrazykline) sind antibiotisch wirksame Arzneistoffe (Antibiotika), die von verschiedenen Streptomyceten produziert werden. Tetracycline führen zu einer Hemmung der bakteriellen Proteinsynthese an deren Ribosomen und hemmen somit… …   Deutsch Wikipedia

  • Tetracycline — Tétracycline Tétracycline Général No CAS …   Wikipédia en Français

  • Tétracycline — Général No CAS …   Wikipédia en Français

  • tétracycline — [ tetrasiklin ] n. f. • 1954; de tétra, cycle et ine ♦ Méd. Antibiotique à large spectre d action, produit par une espèce de streptomycète ou obtenu par synthèse et dont les dérivés sont utilisés en thérapeutique. ● tétracycline nom féminin… …   Encyclopédie Universelle

  • Tetracycline — Tetracycline,   Tetrazykline, von Bakterien der Gattung Streptomyces (v. a. Streptomyces aureofaciens und Streptomyces rimosus) gewonnene, oral wirksame Antibiotika, die als Grundgerüst ein Ringsystem aus vier kondensierten Sechsringen mit… …   Universal-Lexikon

  • Tetracycline — См. Тетрациклин (Источник: «Словарь терминов микробиологии») …   Словарь микробиологии

  • tetracycline — 1952, with chemical suffix INE (Cf. ine) (2) + tetracyclic “containing four fused hydrocarbon rings,” from TETRA (Cf. tetra ) + cyclic (see CYCLE (Cf. cycle) (n.)) …   Etymology dictionary

  • tetracycline — [te΄trə sī′klin, te΄trə sī′klēn΄] n. [< TETRA + CYCL(IC) + INE3] a yellow, odorless, crystalline powder, C22H24N2O8, prepared synthetically or obtained from certain streptomyces: it is a broad spectrum antibiotic …   English World dictionary

  • Tetracycline — This article is about the specific antibiotic called tetracycline. For other uses, see tetracycline antibiotics. Tetracycline Systematic (IUPAC) name (4S,6S,12aS) 4 (dimethylamino) 1,4,4a,5,5a,6,11,12a o …   Wikipedia

  • tetracycline — A broad spectrum antibiotic (a naphthacene derivative), the parent of oxytetracycline, prepared from chlortetracycline and also obtained from the culture filtrate of several species of Streptomyces; also available as t. hydrochloride and t.… …   Medical dictionary

  • Tetracycline — Химическая структура молекулы тетрациклина Тетрациклин (Tetracycline)  антибиотик из группы тетрациклинов. Содержание 1 Фармакологическое действие 2 …   Википедия


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