BCG vaccine


BCG vaccine
Immunol.
a vaccine made from weakened strains of tubercle bacilli, used to produce immunity against tuberculosis.
[1925-30; B(ACILLUS) C(ALMETTE-)G(UÉRIN)]

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   vaccine against tuberculosis. The BCG vaccine is prepared from a weakened strain of Mycobacterium bovis, a bacteria closely related to M. tuberculosis, which causes the disease. The vaccine was developed over a period of 13 years, from 1908 to 1921, by French bacteriologists Albert Calmette (Calmette, Albert) and Camille Guérin (Guérin, Camille), who named the product Bacillus Calmette-Guérin, or BCG. The vaccine is administered shortly after birth only in infants at high risk of tuberculosis. BCG vaccine produces an immune response that partly protects infants and young children from serious forms of tuberculosis. Because of the risk of infection and variability in protection associated with the vaccine, it is used only in countries where the prevalence of tuberculosis is high.

      For a variable number of years after BCG vaccination, many people show a local skin reaction to the purified protein derived skin test (also called tuberculin skin test). Further testing for tuberculosis is often required in individuals given BCG vaccination in order to distinguish between a false-positive test result, in which an individual is not infected with tuberculosis, and a positive test result, in which an individual is infected with tuberculosis.

John Hansen-Flaschen
 

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Universalium. 2010.

Look at other dictionaries:

  • BCG vaccine — bē (.)sē jē n a vaccine prepared from a living attenuated strain of tubercle bacilli and used to vaccinate human beings against tuberculosis A. L. C. Calmette and C. Guérin see BACILLUS CALMETTE GUÉRIN * * * [USP] [bacille Calmette Guйrin] a vac …   Medical dictionary

  • BCG (vaccine) — or BCG n. 〚b( acillus) C( almette ) G( uérin), after A. L. C. Calmette (1863 1933) & Camille Guérin (1872 1961), Fr physicians who developed it〛 a vaccine prepared from an attenuated strain of the tubercle bacillus, used for immunization against… …   Universalium

  • BCG (vaccine) — or BCG n. [b( acillus) C( almette ) G( uérin), after A. L. C. Calmette (1863 1933) & Camille Guérin (1872 1961), Fr physicians who developed it] a vaccine prepared from an attenuated strain of the tubercle bacillus, used for immunization against… …   English World dictionary

  • BCG (vaccine) — or BCG n. [b( acillus) C( almette ) G( uérin), after A. L. C. Calmette (1863 1933) & Camille Guérin (1872 1961), Fr physicians who developed it] a vaccine prepared from an attenuated strain of the tubercle bacillus, used for immunization against… …   English World dictionary

  • BCG vaccine — noun Etymology: Bacillus Calmette Guérin (an attenuated strain of tubercle bacilli), from Albert Calmette died 1933 and Camille Guérin died 1961 French bacteriologists Date: 1927 a vaccine prepared from a living attenuated strain of tubercle… …   New Collegiate Dictionary

  • bcg vaccine — |bēˌsēˈjē noun Usage: usually capitalized B&C&G : a vaccine prepared from a living attenuated strain of tubercle bacilli and used to vaccinate human beings against tuberculosis * * * Immunol. a vaccine made from weakened strains of tubercle… …   Useful english dictionary

  • BCG vaccine — n. imu a vaccine made from weakened strains of tubercle bacilli, used to produce immunity against tuberculosis • Etymology: 1925–30; B(acillus)C(almette) G(uérin) …   From formal English to slang

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