ampicillin


ampicillin
/am'peuh sil"in/, n. Pharm.
a broad-spectrum semisynthetic penicillin, C16H19N3O4S, effective against certain susceptible Gram-positive and Gram-negative bacteria.
[1965-70; prob. am(inobenzyl)p(en)icillin, an alternate chemical name]

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drug
      drug used in the treatment of various infections, including otitis media (middle ear infection), sinusitis, and acute bacterial cystitis. Ampicillin (or alpha-aminobenzylpenicillin) is a semisynthetic penicillin, one of the first such antibiotics (antibiotic) developed. Similar in action to penicillin G but more effective against gram-negative bacteria, ampicillin is more stable in stomach acids and therefore may be given orally.

      The potential side effects of ampicillin are similar to those of other penicillins—i.e., chiefly allergic reactions (allergy) ranging from skin rashes and hives to life-threatening anaphylactic shock (anaphylaxis) (very rare). People who are allergic to other drugs in this family are also likely to react to ampicillin. The incidence of skin rash is higher with ampicillin than with other penicillins, a factor that suggests a possible toxic reaction as well as a truly allergic response.

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Universalium. 2010.

Look at other dictionaries:

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  • ampicillin — n. 1. a semisynthetic penicillin which can be considered as the common benzylpenicillin containing an amino group at the alpha benzyl position. Note: It is more active against certain gram negative bacteria than is benzylpenicillin. It found wide …   The Collaborative International Dictionary of English

  • Ampicillin — См. Ампициллин (Источник: «Словарь терминов микробиологии») …   Словарь микробиологии

  • ampicillin — [am΄pə sil′in] n. a synthetic antibiotic, C16H19N3O4S, derived from penicillin, having resistance to acids so that it can be taken orally to fight a wide range of bacterial infections …   English World dictionary

  • Ampicillin — Strukturformel Allgemeines Freiname Ampicillin …   Deutsch Wikipedia

  • ampicillin — Penicillin derivative with broad spectrum activity; ampicillin resistance is often used as a marker for plasmid transfer in genetic engineering (eg. pBR322 is ampicillin resistant) …   Dictionary of molecular biology

  • Ampicillin — Am|pi|cil|lin [Kurzw. aus 6 (α Amino α phenylacetamido)penicillansäure], das; s: Freiname für ein halbsynthetisches Derivat des Penicillins. * * * Ampicillin   das, s, Penicilline …   Universal-Lexikon

  • ampicillin — noun Etymology: amino + penicillin Date: 1961 a penicillin C16H19N3O4S that is effective against gram negative and gram positive bacteria and is used to treat various infections of the urinary, respiratory, and …   New Collegiate Dictionary

  • ampicillin — noun /æm.pɪ sɪ lɪn/lang=en A broad spectrum antibiotic having a beta lactam structure …   Wiktionary

  • ampicillin — An acid stable semisynthetic penicillin derived from 6 aminopenicillanic acid; it has a broader spectrum of antimicrobial action than penicillin G, inhibits the growth of Gram positive and Gram negative bacteria, and is not resist …   Medical dictionary


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