Thomas, E. Donnall

Thomas, E. Donnall

▪ American physician
in full  Edward Donnall Thomas  
born March 15, 1920, Mart, Texas, U.S.

      American physician who in 1990 was corecipient (with Joseph E. Murray (Murray, Joseph E.)) of the Nobel Prize for Physiology or Medicine for his work in transplanting bone marrow (bone marrow transplant) from one person to another—an achievement related to the treatment of patients with leukemia and other blood cancers or blood diseases.

      Thomas studied at the University of Texas (B.A., 1941; M.A., 1943) and the Harvard Medical School (M.D., 1946). He served at a few hospitals and a research centre before becoming a professor of medicine at Columbia University's College of Physicians and Surgeons (1955–63) and the University of Washington School of Medicine (from 1963) in Seattle, where he was also associated with the Fred Hutchinson Cancer Research Center.

      In 1956 Thomas performed the first successful bone marrow transplant between two humans: a leukemic patient and his identical twin. The recipient's body accepted the donated marrow and used it to make new, healthy blood cells and immune system cells. Thomas adopted methods to match the tissues of donor and recipient closely enough to minimize the latter's rejection of the former's marrow, and he also developed drugs to suppress the immune system. In 1969 these refinements enabled him to perform the first successful bone marrow transplant in a leukemia patient from a relative who was not an identical twin. Before his work, leukemia had invariably been a fatal disease. By 1990, partially as a result of his research, more than half of all leukemia patients could be expected to survive.

      In 1990 Thomas was awarded the U.S. National Medal of Science. Thomas also wrote several books during his career, including Aplastic Anemia (1978), Frontiers on Bone Marrow Transplantation: Fetal Hematopoiesis (1991), and Hematopoietic Cell Transplantation (1999; cowritten with Stephen J. Forman and Karl G. Blume).

* * *


Universalium. 2010.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • Thomas , Edward Donnall — (1920–) American physician Thomas was born at Mart in Texas and educated at the University of Texas, receiving his BA in 1941 and MA two years later. In 1946 he was awarded his MD by Harvard University. He worked at the Peter Bent Brigham… …   Scientists

  • Thomas — Edward Donnall …   Scientists

  • Thomas I. — Thomas ist ein männlicher Vorname, der auch als Nachname eine nennenswerte Verbreitung hat. Herkunft und Bedeutung des Namens Der Name stammt aus dem aramäischen te oma (תאומא) und bedeutet „Zwilling“. So wird er auch im Johannesevangelium[1]… …   Deutsch Wikipedia

  • Thomas (Familienname) — Thomas ist ein Familienname. Zur Etymologie des Namens siehe unter Thomas. Namensträger Inhaltsverzeichnis A B C D E F G H I J K L M N O P Q R S T U V W X …   Deutsch Wikipedia

  • Thomas — (izg. tȍmas) DEFINICIJA 1. Dylan Marlais (1914 1953), engleski pjesnik i prozni pisac iz Walesa, poznat po bogatom, maštovitom izrazu, patosu, dramatskoj karakterizaciji i specifičnom humoru; introspektivan diskurs pun lucidne energije, teme… …   Hrvatski jezični portal

  • E. Donnall Thomas — Donnall Edward (Don) Thomas Born March 15, 1920 (1920 03 15) (age 91) …   Wikipedia

  • Donnall Thomas — Donall Thomas Naissance 15 mars 1920 (États Unis) Nationalité américaine Champs Médecine et immunologie …   Wikipédia en Français

  • Thomas — Tho|mas [nach dem Apostel Thomas, vgl. Joh. 20, 24–29]: in der Fügung ungläubiger T. (Mensch, der nicht bereit ist, etw. zu glauben, wovon er sich nicht selbst überzeugt hat). * * * I Thomas,   Neues Testament: ein Jünger Jesu, einer der zwölf …   Universal-Lexikon

  • Thomas — I. noun Etymology: Greek Thōmas, from Hebrew t ōm twin Date: before 12th century an apostle who demanded proof of Jesus resurrection II. biographical name (Charles Louis ) Ambroise 1811 1896 French composer III. biographical name Augustus 1857… …   New Collegiate Dictionary

  • E. Donnall Thomas — Edward Donnall Thomas (* 15. März 1920 in Mart (bei Waco), Texas, USA) ist ein US amerikanischer Nobelpreisträger für Medizin, emeritierter Professor der University of Washington in Seattle. 1980 wurde er mit dem Charles F. Kettering Prize der… …   Deutsch Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”