Huggins, Charles B.

Huggins, Charles B.

▪ American surgeon and medical researcher
in full  Charles Brenton Huggins  
born Sept. 22, 1901, Halifax, Nova Scotia, Can.
died Jan. 12, 1997, Chicago, Ill., U.S.
 Canadian-born American surgeon and urologist whose investigations demonstrated the relationship between hormones and certain types of cancer. For his discoveries Huggins received (with Peyton Rous (Rous, Peyton)) the Nobel Prize for Physiology or Medicine in 1966.

      Huggins was educated at Acadia University (Wolfville, N.S.) and at Harvard University, where he received his M.D. in 1924. He went to the University of Michigan for further training in surgery (1924–27) and then joined the faculty of the University of Chicago, where he served as director of the Ben May Laboratory for Cancer Research from 1951 to 1969.

      Huggins was a specialist on the male urological and genital tract. In the early 1940s he found he could retard the growth of prostate (prostate cancer) cancer by blocking the action of the patient's male hormones with doses of the female hormone estrogen. This research demonstrated that some cancer cells, like normal body cells, are dependent on hormonal signals to survive and grow and that, by depriving cancer cells of the correct signals, the growth of tumours could be slowed down, at least temporarily. In 1951 Huggins showed that breast cancers (breast cancer) are also dependent on specific hormones. By removing the ovaries and adrenal glands, which are the source of estrogen, he could achieve significant tumour regression in some of his patients. Owing to his work, drugs that block the body's production of estrogen became important resources in treating breast cancer.

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Universalium. 2010.

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  • Huggins, Charles Brenton — ▪ 1998       Canadian born American surgeon and medical researcher (b. Sept. 22, 1901, Halifax, N.S. d. Jan. 12, 1997, Chicago, Ill.), specialized in the surgical and therapeutic treatment of cancer of the prostate and mammary glands and shared… …   Universalium

  • Huggins , Charles Brenton — (1901–) Canadian–American surgeon Huggins, who was born at Halifax in Nova Scotia, was educated at Acadia University and at the Harvard Medical School, where he obtained his MD in 1924. After graduate training at the University of Michigan he… …   Scientists

  • Huggins,Charles Brenton — Hug·gins (hŭgʹĭnz), Charles Brenton. 1901 1997. Canadian born American surgeon. He shared a 1966 Nobel Prize for research in hormone treatment for cancer of the prostate. * * * …   Universalium

  • Huggins, Charles B. — ► (1901 97) Fisiólogo estadounidense. Fue premio Nobel de Medicina y Fisiología en 1966, compartido con F. P. Rous, por sus descubrimientos acerca del tratamiento hormonal del cáncer de próstata …   Enciclopedia Universal

  • Huggins, Charles B(renton) — born Sept. 22, 1901, Halifax, Nova Scotia, Can. died Jan. 12, 1997, Chicago, Ill., U.S. Canadian born U.S. surgeon and urologist. He studied at the University of Chicago and subsequently taught there for several decades. He found that using… …   Universalium

  • Huggins, Charles B(renton) — (22 sep. 1901, Halifax, Nueva Escocia, Canadá–12 ene. 1997, Chicago, Ill., EE.UU.). Cirujano y urólogo estadounidense nacido en Canadá. Estudió en la Universidad de Chicago y enseñó en ella por varias décadas. Descubrió que empleando estrógenos… …   Enciclopedia Universal

  • Huggins — Huggins, Charles B …   Enciclopedia Universal

  • Charles Brenton Huggins — Born September 22, 1901 …   Wikipedia

  • Charles B. Huggins — Charles Brenton Huggins (* 22. September 1901 in Halifax, Kanada; † 12. Januar 1997 in Chicago, USA) war ein kanadisch US amerikanischer Chirurg. Er erhielt 1966 den Nobelpreis für Physiologie oder Medizin für seine „Entdeckungen zur… …   Deutsch Wikipedia

  • Charles Huggins — Charles Brenton Huggins (* 22. September 1901 in Halifax, Kanada; † 12. Januar 1997 in Chicago, USA) war ein kanadisch US amerikanischer Chirurg. Er erhielt 1966 den Nobelpreis für Physiologie oder Medizin für seine „Entdeckungen zur… …   Deutsch Wikipedia

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