Hartwell, Leland H.


Hartwell, Leland H.
born Oct. 30, 1939, Los Angeles, Calif., U.S.

U.S. scientist.

He received his Ph.D. from the Massachusetts Institute of Technology. He began teaching at the University of Washington in 1968 and in 1996 joined the Fred Hutchinson Cancer Research Center, becoming president and director in 1997. Using baker's yeast, he studied how cells control their growth and division and was able to identify more than 100 genes involved in cell-cycle control, including the gene that regulates the first step of each cell cycle. Such work aided in the understanding of cancer cell development. Hartwell shared a Nobel Prize with R. Timothy Hunt and Sir Paul M. Nurse in 2001.

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▪ American scientist
born October 30, 1939, Los Angeles, California, U.S.

      American scientist who, with Sir Paul M. Nurse (Nurse, Sir Paul M.) and R. Timothy Hunt (Hunt, R. Timothy), shared the Nobel Prize for Physiology or Medicine in 2001 for discovering key regulators of the cell cycle.

      Hartwell studied at the California Institute of Technology (B.S., 1961) and the Massachusetts Institute of Technology (Ph.D., 1964). He served on the faculty of the University of California at Irvine from 1965 to 1968, when he moved to the University of Washington. In 1996 he joined the Fred Hutchinson Cancer Research Center in Seattle, Washington, becoming president and director in 1997.

      In the late 1960s Hartwell began using baker's yeast to study how cells control their growth and division. He identified more than 100 genes (gene), termed cell-division-cycle (CDC) genes, involved in cell-cycle control. One such gene, named cdc28, was demonstrated to control the first phase and so became known as “start.” Hartwell also found that the cycle includes optional pauses, called checkpoints, that allow time for repair of damaged DNA. His work helped expand scientific understanding of cancer and other diseases that occur when the machinery of the cell cycle goes awry.

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Universalium. 2010.

Look at other dictionaries:

  • Hartwell, Leland H. — (n. 30 oct. 1939, Los Ángeles, Cal., EE.UU.). Científico estadounidense. Obtuvo su Ph.D. en el Instituto Tecnológico de Massachusetts. En 1968 inició la docencia en la Universidad de Washington y en 1996 se incorporó al Centro Fred Hutchinson… …   Enciclopedia Universal

  • Leland Hartwell — Leland H. Hartwell (* 30. Oktober 1939 in Los Angeles), Biochemiker und Krebsforscher, ist Direktor des Fred Hutchinson Cancer Research Center an der University of Washington in Seattle. Im Jahr 2001 erhielt er gemeinsam mit R. Timothy Hunt und… …   Deutsch Wikipedia

  • Leland — /lee leuhnd/, n. a male given name. * * * (as used in expressions) Cronkite Walter Leland Jr. Hartwell Leland H. Leland Henry Martyn Stanford Amasa Leland * * * …   Universalium

  • Leland — (as used in expressions) Cronkite, Walter (Leland, Jr.) Hartwell, Leland H. Leland, Henry Martyn Stanford, (Amasa) Leland …   Enciclopedia Universal

  • Leland H. Hartwell — Leland Harrison Hartwell Nombre Leland Harrison Hartwell Nacimiento 30 d …   Wikipedia Español

  • Leland H. Hartwell — Leland Harrison Lee Hartwell (* 30. Oktober 1939 in Los Angeles), Biochemiker und Krebsforscher, ist Direktor des Fred Hutchinson Cancer Research Center an der University of Washington in Seattle. Im Jahr 2001 erhielt er gemeinsam mit Tim Hunt… …   Deutsch Wikipedia

  • Hartwell (disambiguation) — Hartwell may refer to:* Hartwell, a village in central Buckinghamshire, England * Hartwell, Northamptonshire, a village in England * Hartwell, Georgia, a city in the United States ** Hartwell Railroad * Hartwell, Victoria, a suburb of Melbourne,… …   Wikipedia

  • Hartwell — ist der Name mehrerer Personen: Barrie Hartwell nordirischer Archäologe Hugh Hartwell (* 1945), kanadischer Komponist und Musikpädagoge Leland H. Hartwell (* 1939), US amerikanischer Biochemiker und Krebsforscher Orte: Hartwell House bei… …   Deutsch Wikipedia

  • Leland — ist der Name folgender Orte in den Vereinigten Staaten: Leland (Illinois) Leland (Iowa) Leland (Louisiana) Leland (Michigan) Leland (Mississippi) Leland (North Carolina) Leland (Wisconsin) Leland Township (Leelanau County, Michigan) Leland River …   Deutsch Wikipedia

  • Leland H. Hartwell — Leland H. (Lee) Hartwell (né le 30 octobre 1939 à Los Angeles (Californie)) est président et directeur du Centre Fred Hutchinson de Recherche sur le Cancer à Seattle (Washington). Il a obtenu le Prix Nobel de Physiologie et Médecine en 2001 pour… …   Wikipédia en Français


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