proline


proline
/proh"leen, -lin/, n. Biochem.
an alcohol-soluble amino acid, C4H9NHCOOH, occurring in high concentration in collagen. Abbr.: Pro; Symbol: P
[1900-05; alter. of PYRROLIDINE]

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One of the nonessential amino acids, found in many proteins, especially collagen.

Because the nitrogen atom of its amino group is part of a ring structure (making it a heterocyclic compound), its chemical properties differ from those of the other amino acids in proteins. It is used in biochemical, nutritional, and microbiological research and as a dietary supplement.

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      an amino acid obtained by hydrolysis of proteins. Its molecule contains a secondary amino group (>NH) rather than the primary amino group (>NH2) characteristic of most amino acids. Unlike other amino acids, proline, first isolated from casein (1901), is readily soluble in alcohol. Collagen, the principal protein of connective tissue, yields about 15 percent proline. It is one of several so-called nonessential amino acids; i.e., animals can synthesize it from glutamic acid and do not require dietary sources.

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Universalium. 2010.

Look at other dictionaries:

  • Proline — L ou S( ) proline   et   D ou R(+) proline …   Wikipédia en Français

  • proline — ● proline nom féminin Acide aminé non essentiel (qui peut être synthétisé par l organisme), présent en abondance dans les protéines. proline [pʀɔlin] n. f. ÉTYM. 1905, → cit.; all. Prolin dû à Fischer et Abderhalden, 1901. → cit. ❖ ♦ Chim., biol …   Encyclopédie Universelle

  • proline — [prō′lēn΄, prō′lin] n. [Ger prolin, contr. < pyrrolidin < pyrrol, PYRROLE + id, IDE + in, INE3] a nonessential amino acid, C4H8N COOH, formed by the decomposition of proteins: see AMINO ACID …   English World dictionary

  • Proline — For other uses, see Proline (disambiguation). Proline …   Wikipedia

  • proline — (= pro; P; 115D) One of the 20 amino acids directly coded for in proteins. Structure differs from all the others, in that its side chain is bonded to the nitrogen of the a amino group, as well as the a carbon. This makes the amino group a… …   Dictionary of molecular biology

  • proline — Pyrrolidine 2 carboxylic acid; the l isomer is found in proteins, especially the collagens. SYN: pyrrolidine 2 carboxylate. p. aminopeptidase SYN: p. iminopeptidase. p. dehydrogenase SYN: pyrroline 2 carboxylate reductase, pyrroline 5 carboxylate …   Medical dictionary

  • proline — prolinas statusas T sritis chemija formulė NC₄H₈COOH santrumpa( os) Pro, P atitikmenys: angl. proline rus. пролин ryšiai: sinonimas – 2 pirolidinkarboksirūgštis …   Chemijos terminų aiškinamasis žodynas

  • proline — noun Etymology: German Prolin, contraction of Pyrrolidin pyrrolidine (C4H9N), from International Scientific Vocabulary pyrrole + idine Date: 1904 an amino acid C5H9NO2 that can be synthesized by animals from glutamate …   New Collegiate Dictionary

  • proline — noun A nonessential amino acid CHNO found in most animal proteins, especially collagen; its cyclic structure leads to kinks in the peptide chain of proteins. Syn: Pro …   Wiktionary

  • proline — n. amino acid found in collagen …   English contemporary dictionary


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