primaquine


primaquine
/pruy"meuh kween'/, n. Pharm.
a viscous liquid, C15H21N3O, used in the treatment of malaria.
[1945-50; < NL prima PRIME + QUIN(OLIN)E]

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drug
      synthetic drug used in the treatment of malaria, an infection caused by the protozoan parasite Plasmodium transmitted to humans by the bite of various species of Anopheles mosquitoes. Introduced into medicine in the 1950s, primaquine is one of an important series of chemically related antimalarial agents, the quinoline derivatives. It is administered orally as primaquine phosphate.

      Primaquine inhibits the development of the malarial parasites Plasmodium vivax and P. ovale in both blood and tissue, thus curing the disease and preventing relapses. Some abdominal discomfort may occur as a side effect.

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Universalium. 2010.

Look at other dictionaries:

  • Primaquine — Systematic (IUPAC) name (RS) N (6 methoxyquinolin 8 yl)pentane 1,4 diamine Clinical data AHFS/Drugs.com …   Wikipedia

  • primaquine — ☆ primaquine [prī′mə kwēn΄ ] n. [< L primus, first (see PRIME) + QU(IN)INE] a synthetic chemical compound, C15H21N3O, used as a cure for malaria …   English World dictionary

  • primaquine — An 8 aminoquinoline drug used to treat malaria. Affects the mitochondria of the exo erythrocytic stages (see Plasmodium), but the mechanism is not understood. The most effective drug at preventing spread of all four species of human malaria …   Dictionary of molecular biology

  • primaquine — noun A medication used in the treatment of malaria and Pneumocystis pneumonia …   Wiktionary

  • primaquine — pri·ma·quine prī mə .kwēn, prim ə , kwin n an antimalarial drug used in the form of its diphosphate C15H21N3O·2H3PO4 * * * n. a drug used in the treatment of malaria. It is administered by mouth, usually in combination with other antimalarial… …   Medical dictionary

  • primaquine — n. medication for treating malaria …   English contemporary dictionary

  • primaquine — pri·ma·quine …   English syllables

  • primaquine — n. a drug used in the treatment of malaria. It is administered by mouth after treatment with chloroquine. High doses may cause blood disorders (such as methaemoglobinaemia or haemolytic anaemia) and digestive upsets …   The new mediacal dictionary

  • primaquine — pri•ma•quine [[t]ˈpraɪ məˌkwin[/t]] n. pha a viscous liquid, C15H21N3O, used in the treatment of malaria • Etymology: 1945–50; < NL prīma prime+quin (olin) e …   From formal English to slang

  • primaquine — noun synthetic antimalarial drug • Hypernyms: ↑antimalarial, ↑antimalarial drug …   Useful english dictionary


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