dopamine


dopamine
/doh"peuh meen'/, n.
1. Biochem. a catecholamine neurotransmitter in the central nervous system, retina, and sympathetic ganglia, acting within the brain to help regulate movement and emotion: its depletion may cause Parkinson's disease. Cf. dopa.
2. Pharm. a dopamine preparation used to increase the force of contraction of the heart in the treatment of shock. Cf. levodopa.
[1955-60; see DOPA, AMINE]

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One of the catecholamines, widely distributed in the central nervous system.

Through a series of enzymatic reactions (see enzyme) it is formed from levodopa and converted to norepinephrine and then epinephrine. It is a central nervous system neurotransmitter essential to control of motion; it also acts as a hormone. Degeneration of certain dopamine-producing brain cells results in parkinsonism.

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also called  Hydroxytyramine,  

      a nitrogen-containing organic compound formed as an intermediate compound from dihydroxyphenylalanine (dopa) during the metabolism of the amino acid tyrosine. It is the precursor of the hormones epinephrine and norepinephrine. Dopamine also functions as a neurotransmitter—primarily by inhibiting the transmission of nerve impulses—in the substantia nigra, basal ganglia, and corpus striatum of the brain. A deficiency of dopamine results in Parkinson's disease (parkinsonism) (q.v.).

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Universalium. 2010.

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  • dopamine — [ dɔpamin ] n. f. • 1949; de dopa et amine ♦ Physiol. Amine précurseur de la noradrénaline, indispensable à l activité normale du cerveau. ● dopamine nom féminin Neurotransmetteur du groupe des catécholamines, précurseur de la noradrénaline,… …   Encyclopédie Universelle

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  • dopamine — 1959, from DOPA, the amino acid (from first letter of elements of dioxyphenylalanine), + AMINE (Cf. amine) …   Etymology dictionary

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