Sjögren's syndrome

Sjögren's syndrome

also called  Sicca Syndrome,  

      chronic inflammatory disorder characterized by severe dryness of the eyes and the mouth that results from a diminution in secretion of tears and saliva. Dryness may also involve the nose, pharynx, larynx, and tracheobronchial tree. Approximately half the persons affected also have rheumatoid arthritis or, less commonly, some other connective-tissue disease, such as scleroderma, polymyositis, or systemic lupus erythematosus. The great majority of the persons affected by Sjögren's syndrome are women.

      Infiltration (gradual assemblage) of lymphocytes and plasma cells leads to enlargement of the parotid or other salivary glands in half the patients. There may also be enlargement of the spleen, diminution in white blood cell numbers, Raynaud's phenomenon, vasculitis (inflammation of vessels) with chronic leg ulcers, a disease of the peripheral or trigeminal nerves, chronic (Hashimoto's) thyroiditis (inflammation of the thyroid), enlargement of the liver, and inflammation of the pancreas. A number of persons with sicca syndrome of long duration have developed neoplasms of the type called reticulum cell sarcoma, or primary macroglobulinemia (the presence in the blood of globulins of high molecular weight).

      Treatment toward relief of symptoms includes the administration of artificial tears to lessen ocular dryness. Corticosteroids or immunosuppressive drugs have been employed with some success for the more serious manifestations.

* * *


Universalium. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • Sjögren's syndrome — Classification and external resources Histopathologic image of focal lymphoid infiltration in the minor salivary gland associated with Sjögren s syndrome. Lip biopsy. H E stain. ICD 10 …   Wikipedia

  • Sjogren-Larsson syndrome — The Sjogren Larsson syndrome is a genetic (inherited) disease usually characterized by a triad of clinical findings consisting of ichthyosis (thickened fish like skin), spastic paraplegia (spasticity of the legs) and mental retardation. The skin… …   Medical dictionary

  • Sjögren-Larsson syndrome — Infobox Disease Name = Sjögren Larsson syndrome Caption = DiseasesDB = 30051 ICD10 = ICD10|Q|87|1|q|80 (ILDS Q87.136) ICD9 = ICDO = OMIM = 270200 MedlinePlus = eMedicineSubj = derm eMedicineTopic = 706 MeshID = D016111 Sjögren Larsson syndrome… …   Wikipedia

  • Sjogren's syndrome — Sjö·gren s syndrome also Sjögren syndrome shǣ .gren(z) n a chronic inflammatory autoimmune disease that affects esp. older women, that is characterized by dryness of mucous membranes esp. of the eyes and mouth and by infiltration of the affected… …   Medical dictionary

  • Sjögren's syndrome — an autoimmune condition affecting the salivary and lacrimal glands, resulting in a dry mouth and dryness of the eyes. In the systemic form of the disease other glands may be affected, causing dryness of the airways, vagina, or skin, as well as… …   The new mediacal dictionary

  • sjögren's syndrome — ˈshœ̅grənz noun also sjögren syndrome or sjögren s disease Usage: usually capitalized 1st S Etymology: after H.S.C. Sjögren died 1986 Swedish ophthalmologist : a chronic inflammatory autoimmune disease that affects especially older women, that is …   Useful english dictionary

  • Sjögren's syndrome — noun An autoimmune disorder in which immune cells attack and destroy the exocrine glands that produce tears and saliva. Syn: Mikulicz disease, sicca syndrome …   Wiktionary

  • Sjogren&’s syndrome — One of the so called connective tissue diseases that also include rheumatoid arthritis, systemic lupus erythematosus and rheumatic fever. Characterized by inflammation of conjunctiva and cornea …   Dictionary of molecular biology

  • SLS (Sjogren-Larsson syndrome) — The Sjogren Larsson syndrome is a genetic (inherited) disease usually characterized by a triad of clinical findings consisting of ichthyosis (thickened fish like skin), spastic paraplegia (spasticity of the legs) and mental retardation. The skin… …   Medical dictionary

  • Syndrome de Gougerot-Sjogren — Syndrome de Goujerot Sjögren Syndrome de Goujerot Sjögren CIM 10: M35.0 {{{CIM10}}}.0 {{{X.0}}} …   Wikipédia en Français

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”