transferrin

transferrin
/trans fer"in/, n. Biochem.
a plasma glycoprotein that transports dietary iron to the liver, spleen, and bone marrow.
[1947; TRANS- + L ferr(um) iron + -IN2]

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also called  Siderophilin,  

      protein (beta1 globulin) in blood plasma that transports iron from the tissues and bloodstream to the bone marrow, where it is reused in the formation of hemoglobin. Found fixed to the surface of developing red blood cells, transferrin frees iron directly into the cell. Human beings have 14 different types of transferrin, but all are believed to be determined at a single genetic locus. They are named by letters of the alphabet; the commonest is called C.

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Universalium. 2010.

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  • Transferrin — is a blood plasma protein for iron ion delivery. Transferrin is a glycoprotein, which binds iron very tightly but reversibly. Although iron bound to transferrin is less than 0.1% (4 mg) of the total body iron, dynamically it is the most important …   Wikipedia

  • transferrin — transferrin. См. трансферрин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • transferrin — [trans fer′in] n. [< TRANS + L ferrum, iron (see FERRO ) + IN1] an iron binding, crystalline globulin in blood plasma, that is important as an iron carrier …   English World dictionary

  • Transferrin — Serotransferrin Vorhandene Strukturdaten …   Deutsch Wikipedia

  • Transferrin — A plasma protein that transports iron through the blood to the liver, spleen and bone marrow. The blood transferrin level is tested for diverse reasons: to determine the cause of anemia, to examine iron metabolism (for example, in iron deficiency …   Medical dictionary

  • transferrin — The iron storage protein (80 kD) found in mammalian serum; a b globulin. Binds ferric iron with a Kass of around 21 at pH 7.4, 18.1 at pH 6.6. An important constituent of growth media. Transferrin receptors on the cell surface bind transferrin as …   Dictionary of molecular biology

  • Transferrin — Trans|fer|rin [↑ trans (2), ↑ Ferri u. ↑ in (3)], das; s, e; Syn.: Serum Transferrin, Siderophilin: ein rotes Nichthäm Eisen Protein (MG 79 600) aus 679 Aminosäuren, ca. 6 % Kohlenhydraten (Glykoprotein) u. 2 Fe(III) Ionen. Im Organismus fungiert …   Universal-Lexikon

  • transferrin — transferinas statusas T sritis chemija apibrėžtis Kraujo plazmos glikoproteinas, pernešantis Fe³⁺. atitikmenys: angl. transferrin rus. трансферрин …   Chemijos terminų aiškinamasis žodynas

  • Transferrin-Rezeptor 2 — Masse/Länge Primärstruktur 801/630/774 Aminosäuren (α/β/γ) …   Deutsch Wikipedia

  • Transferrin saturation — Transferrin saturation, measured as a percentage, is a medical laboratory value. It is the ratio of serum iron and total iron binding capacity, multiplied by 100. For an explanation of some clinical situations in which this ratio is important,… …   Wikipedia

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