hyaluronidase

hyaluronidase
/huy'euh loo ron"i days', -dayz'/, n.
1. Biochem. a mucolytic enzyme found in the testes, in snake venom, and in hemolytic streptococci and certain other bacteria, that decreases the viscosity of the intercellular matrix by breaking down hyaluronic acid.
2. Pharm. a commercial form of this substance, used chiefly to promote the diffusion of intradermally injected drugs.
[1935-40; HYALURON(IC) + -id- (by analogy with AMIDASE, PEPTIDASE, etc.) + -ASE]

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▪ enzyme
      any of a group of enzymes that catalyze the hydrolysis (chemical decomposition involving the elements of water) of certain complex carbohydrates such as hyaluronic acid and chondroitin sulfates. The enzymes have been found in insects, leeches, snake venom, mammalian tissues (testis being the richest mammalian source), and in bacteria.

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Universalium. 2010.

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  • Hyaluronidase — Bezeichner Gen Name …   Deutsch Wikipedia

  • hyaluronidase — ● hyaluronidase nom féminin Enzyme diminuant la viscosité des milieux riches en acide hyaluronique …   Encyclopédie Universelle

  • hyaluronidase — [hī΄əl o͞orän′i dās΄] n. [< HYALURONIC ACID + ID(E) + ASE] an enzyme that inactivates hyaluronic acid by breaking down its polymeric structure, thus promoting the diffusion of substances through tissues: found in sperm cells, certain venoms… …   English World dictionary

  • Hyaluronidase — drugbox IUPAC name = Sheep hyaluronidase CAS number = 488712 31 8 ATC prefix = B06 ATC suffix = AA03 ATC supplemental = PubChem = DrugBank = BTD00022 C=2455 | H=3775 | N=617 | O=704 | S=21 molecular weight = 53870.9 g/mol bioavailability =… …   Wikipedia

  • Hyaluronidase — Les hyaluronidases (EC 3.2.1.35) sont une classe d enzymes qui dégradent les acides hyaluroniques En catalysant l hydrolyse des acides hyaluroniques, des composants majeurs des liaisons inter cellulaires, les hyaluronidases abaissent la viscosité …   Wikipédia en Français

  • hyaluronidase — 1. Term used loosely for hyaluronate lyase, hyaluronoglucosaminidase, and hyaluronoglucuronidase, one or more of which are present in testis, sperm, other organs, bee and snake venoms, type II pneumonococci, certain hemolytic …   Medical dictionary

  • hyaluronidase — n. an enzyme that depolymerizes hyaluronic acid and therefore increases the permeability of connective tissue. Hyaluronidase is found in the testes, in semen, and in other tissues …   The new mediacal dictionary

  • Hyaluronidase deficiency — (also known as Mucopolysaccharidosis type IX ) is a condition caused by mutations in HYAL1, and characterized by multiple soft tissue masses.[1]:544 See also Morquio syndrome Hunter syndrome Hurler syndrome Skin lesion References …   Wikipedia

  • hyaluronidase — noun Etymology: International Scientific Vocabulary, from hyaluronic (acid) + idase (as in glucosidase) Date: 1940 a mucolytic enzyme that facilitates the spread of fluids through tissues by lowering the viscosity of hyaluronic acid …   New Collegiate Dictionary

  • hyaluronidase — Enzyme that degrades hyaluronic acid; found in lysosomes …   Dictionary of molecular biology

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